Humanized Mouse Versus Non-human Primate Models of HIV-1 Infection
作者： Qingsheng Li , Charles Wood
DOI: 10.1007/978-1-4939-1655-9_17
关键词:
摘要: Animal models are critical for biomedical research including human immunodeficiency virus type one (HIV-1). Asian non-human primate (NHP) macaques and humanized mice (hu-mice) the two best available of HIV-1 infection humans. Here, we compare contrast pros cons NHP hu-mouse humans in general; discuss detail which model is more relevant studying transmission vaccine, what aspects these need to be further improved order meet need.
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