Use of high dose concentrations of gaseous nitric oxide

作者: Douglas R. Hole , Robert E. Lee , Christopher C. Miller

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摘要: The invention relates to a methods and devices of delivering gaseous nitric oxide mammal or surface at concentration ranging from about 1000 ppm 50,000 oxide. Different conditions which can be treated by high dosage administration gNO include but are not limited to: topical treatments with gNO, cosmetic applications vasodilation inhalation the blood treatment skin tissue infections inflammation on within body, biofilms gNO. Other conditions, aliments, symptoms that may bronchoconstriction, reversible pulmonary vasoconstriction, asthma, hypertension, adult respiratory distress syndrome (ARDS), persistent hypertension newborn (PPHN).

参考文章(87)
Oscar G. Stivala, Hyperbaric treatment apparatus ,(1978)
U. Pison, K. J. Falke, R. Rossaint, H. Gerlach, Inhaled nitric oxide: its effects on pulmonary circulation and airway smooth muscle cells. European Heart Journal. ,vol. 14, pp. 133- 140 ,(1993)
Anthony V. Beran, Medical corrugated respiratory tube ,(1980)
Doug Hole, Bruce Murray, Ali Ardakani, Abdi Ghaffari, Chris Miller, Use of exogenous gaseous nitric oxide in the treatment and disinfection of biofilms ,(2004)
Stephen T. Wellinghoff, Joel J. Kampa, Sumner A. Barenberg, Darren E. Barlow, Compositions for sustained release of a gas ,(1998)