Kntc2 peptides and vaccines containing the same
作者： Tomohisa Watanabe , Sachiko Yoshimura , Ryuji Osawa , Takuya Tsunoda
DOI:
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摘要: Peptide vaccines against cancer are described herein. In particular, isolated epitope peptides derived from the KNTC2 gene that elicit CTLs and thus suitable for use in context of immunotherapy provided. The inventive encompass both -derived modified versions thereof, which one, two, or several amino acids substituted, deleted, inserted added, provided such retain requisite CTL inducibility original sequences. Further polynucleotides encoding as well pharmaceutical compositions include any active agents. Antigen-presenting cells target peptides, methods inducing antigen-presenting cell, also Furthermore, present invention provides treatment and/or prophylaxis (i.e., prevention) cancers (tumors), prevention a metastatic- post-operative recurrence CTLs, anti-tumor immunity, using KNTC2, presenting invention.
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