Serum 25-hydroxyvitamin D is associated with insulin resistance independently of obesity in children ages 5-17.
作者： Emrah Gün , Hakan Uzun , Semih Bolu , İlknur Arslanoğlu , Kenan Kocabay
DOI: 10.1016/J.PCD.2020.06.006
关键词:
摘要: Abstract Aim To determine the association of vitamin D with insulin resistance and obesity in children. Methods A total 92 obese 58 non-obese children aged 5–17 years were evaluated. Data collected related to anthropometric (weight, height), biochemical parameters (fasting plasma glucose, serum insulin, 25-hydroxyvitamin D, lipid profile, B12, parathormone) physical examination (blood pressure, acanthosis nigricans, stria, lipomastia). Insulin (IR) was calculated using homeostasis model assessment (HOMA). HOMA-IR = fasting level (μU/ml) × glucose (mg/dL)/405. value >2.5 defined as resistance. Results According US Endocrine Society classification, deficiency (0−20 ng/ml) determined at significantly higher rates group than control (p Conclusion The prevalence compared normal-weight overweight Serum 25(OH)D levels showed a negative correlation HOMA-IR. is associated independently obesity.
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