摘要: Through novel methodologies, including both basic and clinical research, progress has been made in the therapy of solid cancer. Recent innovations anticancer therapies, immune checkpoint inhibitor biologics, therapeutic vaccines, small drugs, CAR-T cell injections, mark a new epoch cancer already known for faster (epi-)genomics, transcriptomics, proteomics. As long-sought after personalization therapies comes to fruition, need evaluate all current possibilities select best each patient is paramount importance. This task medical care that deserves prominence considerations future. because complex genetic disease. In its deadly form, metastatic cancer, it includes altered genes (and their regulators) encode ten hallmarks cancer-independent growth, dodging apoptosis, immortalization, multidrug resistance, neovascularization, invasiveness, genome instability, inflammation, deregulation metabolism, avoidance destruction by system. These factors have targets many drugs treatments, modulation goal, with hope rendering chronic rather than this article, arsenal against cancers reviewed focus on immunotherapies.
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