Design, Synthesis, and Evaluation of Opioid Analogues with Non-Peptidic β-Turn Scaffold: Enkephalin and Endomorphin Mimetics
作者： Masakatsu Eguchi , Richard Y. W. Shen , J. Paul Shea , Min S. Lee , Michael Kahn
DOI: 10.1021/JM0155897
关键词:
摘要: We have identified a μ-selective opioid receptor agonist without cationic amino group in the molecule from libraries of bicyclic β-turn peptidomimetics. The biologically active conformation lead is proposed to mimic an endomorphin type III 4 → 1 conformation.
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sci-hub.se 参考文章(28)
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