Thermoresponsive Micellization of Poly(ethylene glycol)-b-poly(N-isopropylacrylamide) in Water

摘要: Thermoresponsive micellization of poly(ethylene glycol)-b-poly(N-isopropylacrylamide) (PEG110-b-PNIPAM44) in water is studied by static light scattering and dynamic scattering. The critical aggregation temperature PEG110-b-PNIPAM44 a little higher than homopolymer PNIPAM, it depends on the block copolymer concentration, which increases from 33.7 to 38.4°C when concentration decreases 2.0 0.20 mg/mL. Above temperature, thermoresponsive occurs, resultant spherical micelles consist PNIPAM core PEG shell. exerts strong influence size structure micelles. Micellization at favors formation narrowly distributed, small, dense micelles, while large, loose or micellar clusters form lower concentration.