Risk of infectious complications associated with blood transfusion in elective spinal surgery—a propensity score matched analysis

摘要: Abstract Background Context Although the negative aspects of blood transfusion are increasingly recognized, less is known about transfusion-related risks in spinal surgery. Purpose This study was designed to determine whether perioperative allogeneic associated with increased risk infectious complications after elective Study Design A retrospective cohort propensity score matched analysis carried out. Patient Sample Data patients canal stenosis and spondylolisthesis who underwent lumbar surgeries (decompression or fusion) were obtained from Diagnosis Procedure Combination database, a nationwide administrative inpatient database Japan. Outcome Measures Clinical outcomes included in-hospital death occurrence (surgical site infection [SSI], respiratory tract infection, urinary sepsis). Methods Patients' clinical information, including sex, age, type hospital, preoperative comorbidities, duration anesthesia, cell saver use, volume transfused, investigated. Patients transfused >840 mL (6 units) excluded. Propensity scores for receiving calculated, one-to-one matching based on estimated adjust patients' baseline characteristics. The proportions compared without transfusions. funded by grants Ministry Health, Labour Welfare, Results Of 84,650 identified, 5,289 (6.1%) received transfusions, 4,436 (5.2%) up 840 mL. One-to-one resulted 4,275 pairs transfusion. at SSI (odds ratio [OR], 1.9; 95% confidence interval [CI], 1.4–2.5; p Conclusions Allogeneic surgery infection.