作者: Janne Marvola
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摘要: 3 Abstract Marvola, J. 2008. Neutron Activation-based Gamma Scintigraphic Imaging and Scintigraphy-based Pharmacokinetic Modelling of Per Oral Controlled Release Drug Delivery Dissertationes bioscientiarum molecularium Universitatis Helsingiensis in Viikki, 22/2008, xx pp., ISBN 978952-10-4684-1 (paperback), 978-952-10-4685-8 (PDF), ISSN 1795-7079 The per oral route administration is the most convenient commonly used means drug administration. However, many drugs are ineffectively absorbed orally, or dosing frequency inconveniently short. Controlled-release (CR) technologies offer to optimize resulting plasma concentration-time profiles