Lac repressor-operator complex.
作者： Michele A Kercher , Ponzy Lu , Mitchell Lewis
DOI: 10.1016/S0959-440X(97)80010-3
关键词:
摘要: For many years the lac operon of Escherichia coli has been paradigm for gene regulation. Recently, structures repressor core bound to isopropyl-beta-D-1-thiogalactoside (IPTG), intact apo repressor, complexes with IPTG and a 21-base-pair symmetric operator, refined headpiece have determined. These provided framework understanding wealth biochemical genetic information. An analysis these structures, as well description their function comparison homologous proteins, is now possible.
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