The histologic border zone of acute myocardial infarction--islands or peninsulas?

摘要: Observation of isolated islands apparently surviving myocardium within areas necrotic tissue at the edge myocardial infarctions has been interpreted by some as histologic evidence a unique "border zone" region. Serial section reconstruction transmural canine was performed in this study to establish whether these were truly or continuous peninsulas separated plane section. Three-dimensional analysis infarcts revealed no true but instead demonstrated region composed highly complex interdigitating peninsulas. We conclude that there is an extremely irregular sharp boundary demarcating normal and infarcted with intermediate zone. This observation discussed relation recent data, based on coronary blood flow creatine phosphokinase analysis, which also demonstrates between infarct zones.