Nonsurgical management of Peyronie's disease.

摘要: Peyronie’s disease is not a rare disorder, and it can be devastating to the affected man. Although gold-standard treatment of surgery in stable phase, nonoperative management preferred by some men only option acute phase disease, when contraindicated. No oral or topical therapy has been shown efficacious administered alone, but evidence supports their use as part combination regimen. Intralesional therapies, particularly collagenase clostridium histolyticum (CCH), have promise. Mechanical therapies provide benefit applied for prolonged periods time, improving penile curvature, indentation, even restoring length. Regardless modality chosen, patient counselling paramount, recovery penis its predisease state highly unlikely. Thus, although many options exist nonsurgical remains best who desire most reliable rapid pathway functionally straight, erect penis. The goal should scientifically feasible, safe approach prevent progression of, reduce, deformity improve sexual function. Nonoperative In this Review, Tsambarlis Levine discuss that recommendations use.