Elasticity Measurement of Zona Pellucida Using a Micro Tactile Sensor to Evaluate Embryo Quality
作者： Yoshinobu Murayama , Mitsutoshi Yoshida , Jinji Mizuno , Hiroko Nakamura , Sumiko Inoue
DOI: 10.1274/JMOR.25.8
关键词:
摘要: ABSTRACT To enable improved success rates of IVF, we developed the technology to optimize embryo selection with highest implantation potential while ensuring no damage embryos using zona elasticity as criterion. In this communication outline biomechanics and safety pellucida (ZP) measurement micro tactile sensor (MTS) system demonstrate specific changes in ZP during oocyte maturation, fertilization, early development. Zona hardening was demonstrated mechanically following fertilization at pronuclear (PN) stage, Young's modulus decreased gradually developed. Evaluation quality expanded blastocysts (EPB) showed that EPBs could also be evaluated from parameters. Furthermore, observations indicated ZPs generated vivo were significantly harder than those vitro each stage. Preliminary results denuded...
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