作者: Porntippa Lekcharoensuk
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摘要: HPAI (H5N1) is still an important emerging disease posing threat on both human and animal health. The causative agent continues to evolve rapidly within various poultry populations may cause unpredictable outcome. Evolution of the virus will continue until it reaches equilibrium. At present, viruses possess avian characteristics. However, if gain opportunities infect in human, accelerate adaptation be more preference thus acquires ability transmit efficiently among population. This review aims elucidate crucial issues regarding role vaccination evolution including influence immune response after cross species. Additionally, control drawback vaccine usage are discussed.