Porcine Reproductive and Respiratory Syndrome Modified Live Virus Vaccine: A "Leaky" Vaccine with Debatable Efficacy and Safety.

作者: Lei Zhou , Xinna Ge , Hanchun Yang , None

DOI: 10.3390/VACCINES9040362

关键词:

摘要: … virus (MLV) vaccine, the first commercial PRRS vaccine, was launched in the United States in 1994 [24]. Then, the PRRS MLV vaccine … ), and it is the major commercial vaccine that can …

参考文章(163)
Gourapura J Renukaradhya, Xiang-Jin Meng, Jay G Calvert, Michael Roof, Kelly M Lager, Inactivated and subunit vaccines against porcine reproductive and respiratory syndrome: Current status and future direction. Vaccine. ,vol. 33, pp. 3065- 3072 ,(2015) , 10.1016/J.VACCINE.2015.04.102
Amy Galliher-Beckley, Xiangdong Li, John T. Bates, Rachel Madera, Andrew Waters, Jerome Nietfeld, Jamie Henningson, Dongsheng He, Wenhai Feng, Ruiai Chen, Jishu Shi, Pigs immunized with Chinese highly pathogenic PRRS virus modified live vaccine are protected from challenge with North American PRRSV strain NADC-20. Vaccine. ,vol. 33, pp. 3518- 3525 ,(2015) , 10.1016/J.VACCINE.2015.05.058
Sanipa Suradhat, Piya Wongyanin, Sawang Kesdangsakonwut, Komkrich Teankum, Mongkol Lumyai, Sittikorn Triyarach, Roongroje Thanawongnuwech, A novel DNA vaccine for reduction of PRRSV-induced negative immunomodulatory effects: A proof of concept. Vaccine. ,vol. 33, pp. 3997- 4003 ,(2015) , 10.1016/J.VACCINE.2015.06.020
Gourapura J. Renukaradhya, Xiang-Jin Meng, Jay G. Calvert, Michael Roof, Kelly M. Lager, Live porcine reproductive and respiratory syndrome virus vaccines: Current status and future direction Vaccine. ,vol. 33, pp. 4069- 4080 ,(2015) , 10.1016/J.VACCINE.2015.06.092
Li Gao, Lianghai Wang, Chen Huang, Longlong Yang, Xue-Kun Guo, Zhibin Yu, Yihao Liu, Peng Yang, Wen-hai Feng, HP-PRRSV is attenuated by de-optimization of codon pair bias in its RNA-dependent RNA polymerase nsp9 gene. Virology. ,vol. 485, pp. 135- 144 ,(2015) , 10.1016/J.VIROL.2015.07.012
M M Lai, R S Baric, S Makino, J G Keck, J Egbert, J L Leibowitz, S A Stohlman, Recombination between nonsegmented RNA genomes of murine coronaviruses. Journal of Virology. ,vol. 56, pp. 449- 456 ,(1985) , 10.1128/JVI.56.2.449-456.1985
K. Kupferschmidt, Risk of ‘leaky’ vaccines debated Science. ,vol. 349, pp. 461- 462 ,(2015) , 10.1126/SCIENCE.349.6247.461
Andrew F. Read, Susan J. Baigent, Claire Powers, Lydia B. Kgosana, Luke Blackwell, Lorraine P. Smith, David A. Kennedy, Stephen W. Walkden-Brown, Venugopal K. Nair, Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens PLOS Biology. ,vol. 13, pp. e1002198- ,(2015) , 10.1371/JOURNAL.PBIO.1002198
M M Lai, RNA recombination in animal and plant viruses. Microbiological Research. ,vol. 56, pp. 61- 79 ,(1992) , 10.1128/MR.56.1.61-79.1992
Masaya Tsukamoto, Satoshi Hiroi, Kazuhide Adachi, Hidenori Kato, Marie Inai, Itsuro Konishi, Masaru Tanaka, Ryouhei Yamamoto, Masaki Sawa, Ekowati Handharyani, Yasuhiro Tsukamoto, Antibodies against swine influenza virus neutralize the pandemic influenza virus A/H1N1. Molecular Medicine Reports. ,vol. 4, pp. 209- 214 ,(2011) , 10.3892/MMR.2011.410