Cyclic AMP and Cell Behavior in Cultured Cells

作者: Mark C. Willingham

DOI: 10.1016/S0074-7696(08)61652-6

关键词:

摘要: Publisher Summary The studies reviewed in this chapter make it clear that adenosine 3 ' ,5 -monophosphate (cyclic AMP, cAMP) regulates or affects a great number of the properties cells are measurable culture. multiple effects cAMP probably indicate nature has used molecule for regulatory functions rather frequently. ubiquitous occurrence from bacteria to mammalian cells, and common thread as regulator specific different cell types, points out uniqueness its role. wide variety reactions origins led concept is capable turning on those mechanisms which been genetically programmed. When these undergo malignant change, however, sensitivity control growth reappears, only can overcome go produce tumors.

参考文章(47)
S. C. Pan, W. U. Gardner, Carcinomas of the uterine cervix and vagina in estrogen- and androgen-treated hybrid mice. Cancer Research. ,vol. 8, pp. 337- 345 ,(1948)
V. H. T. James, Luciano Martini, Current topics in experimental endocrinology Academic Press. ,(1971)
John-Gunnar Forsberg, Estrogen, vaginal cancer, and vaginal development American Journal of Obstetrics and Gynecology. ,vol. 113, pp. 83- 87 ,(1972) , 10.1016/0002-9378(72)90456-5
Noboru Takasugi, Howard A. Bern, Tissue Changes in Mice With Persistent Vaginal Cornification Induced by Early Postnatal Treatment With Estrogen2 JNCI: Journal of the National Cancer Institute. ,vol. 33, pp. 855- 865 ,(1964) , 10.1093/JNCI/33.5.855
Arthur F. Kohrman, Robert E. Greenberg, Permanent effects of estradiol on cellular metabolism of the developing mouse vagina Developmental Biology. ,vol. 18, pp. 632- 650 ,(1968) , 10.1016/0012-1606(68)90030-4
JOSEPH T. VELARDO, FREDERICK L. HISAW, ARLEY T. BEVER, INHIBITORY ACTION OF DESOXYCORTICOSTERONE ACETATE, CORTISONE ACETATE, AND TESTOSTERONE ON UTERINE GROWTH INDUCED BY ESTRADIOL-17β1 Endocrinology. ,vol. 59, pp. 165- 169 ,(1956) , 10.1210/ENDO-59-2-165
Cora P Cherry, A Glucksmann, The induction of cervico-vaginal tumours in oestrogenised and androgenised rats British Journal of Cancer. ,vol. 22, pp. 728- 742 ,(1968) , 10.1038/BJC.1968.87
John-Gunnar Forsberg, The effect of estradiol-17-beta on the epithelium in the mouse vaginal anlage. Cells Tissues Organs. ,vol. 63, pp. 71- 88 ,(1966) , 10.1159/000142780
John-Gunnar Forsberg, On the development of the hamster vagina. Cells Tissues Organs. ,vol. 41, pp. 16- 37 ,(1960) , 10.1159/000141603