Compliance with consensus recommendations for the treatment of early stage breast carcinoma in elderly women

摘要: BACKGROUND The goal of this study was to assess variations with age in the management breast carcinoma and identify determinants care received. METHODS A stratified random sample selected among women ≥ 50 newly diagnosed lymph node negative Quebec 1988, 1991, 1993. Information abstracted from medical charts. Predictors definitive locoregional treatment (total mastectomy dissection or breast-conserving surgery both axillary radiation therapy) were identified by multiple logistic regression analysis. RESULTS Overall, 1174 patients years included. Women 70 much less likely receive compared ages 50–69 (48.7% vs. 83.5%; P < 0.0001). Older undergo preservation (76.7% 86.3%; 0.0001), therapy (54.7% 90.5%; nodes (55.6% chemotherapy (1.2% 13.9%; but not tamoxifen (66.4% 64.7%; = 0.41). Adjusting for comorbidity other characteristics related disease, hospital, attending physician, remained a strong determinant probability receiving (odds ratio [OR], 0.14; 95% confidence interval [95% CI], 0.12–0.18 years). The same association observed when who did received systemic adjuvant considered have (OR, 0.13; CI, 0.10–0.17) years). CONCLUSIONS Less aggressive patterns are provided elderly patients, independent comorbidity. This could explain, at least part, sustained mortality population. Cancer 1999;85:1104–13. © 1999 American Society.