The Blood-Retina Barrier
作者： Matthew Campbell , Peter Humphries
DOI: 10.1007/978-1-4614-4711-5_3
关键词:
摘要: The blood-retina barrier (BRB) is composed of both an inner and outer barrier. BRB refers to the formed at retinal pigment epithelial (RPE) cell layer functions, in part, regulate movement solutes nutrients from choroid sub-retinal space. In contrast, BRB, similar blood brain (BBB) located microvasculature comprises microvascular endothelium which line these vessels. tight junctions between cells mediate highly selective diffusion molecules retina essential maintaining homeostasis. this chapter, we summarize key differences iBRB oBRB outline molecular constituents associated with iBRB. We also describe a process for modulation enhance systemic delivery therapeutics retina, technology may pave way safer more effective therapies diseases.
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