Neurophysiology of delirium

摘要: The objective of this thesis was to characterize the neurophysiology delirium and assess whether alterations in delirium, could provide opportunities for detection. In first part thesis, it is shown that by analysis electroencephalogram (EEG) electrocardiogram (ECG) we can expand our knowledge neurophysiological characteristics delirium. Patients with suffer from decreased functional connectivity loss small world topology their EEG when compared patients without These findings are consistent altered network other diseases affect cognitive functioning, such as schizophrenia Alzheimer’s disease. addition, delirious have less complex signals increased spectral variability. reduced complexity corresponds results heart rate variability (HRV) derived ECG, revealed balance between parasympathetic sympathetic activity (sympathovagal balance) may not be during Intensive Care Unit (ICU) second studies assessing detection using EEG, eye movements body temperature were presented. It described several parameters significantly different non-delirium even these measured only two electrodes over a short period time. Furthermore, number movements, especially blinks, had longer duration. Moreover, ICU