Cutaneous manifestations of antiphospholipid syndrome: a review of the clinical features, diagnosis and management.

摘要: Antiphospholipid syndrome is a relatively recent systemic autoimmune disorder defined by thrombotic events and/or obstetric complications in the presence of persistent elevated antiphospholipid antibodies. It\'s characterized wide spectrum clinical presentations and virtually any organ system or tissue may be affected consequences vascular occlusion. Diagnosis sometimes difficult although classification criteria have been published revised there remain ongoing issues regarding nomenclature, expanding features, laboratory tests management much still has to done. Cutaneous manifestations are common frequently first sign disease. Although extremely diverse it\'s important know which dermatological findings should prompt consideration appropriate for those patients. Much debated about when consider consensus does not exist, however spite being diagnostic challenge clinicians look antibodies since an early diagnosis prevent further serious complications. In this article we focus on cutaneous features that raise suspicion complex such Many other signs related described literature but only occasionally without consistency statistic impact therefore will considered here.