An ideal society? Neighbors of diverse origins interact to create and maintain complex mini-organs in the skin.

摘要: The largest organ in the body, skin provides protection against environmental insults and dehydration, is an important gateway for sensory input. In addition to forming barrier, has evolved produce amazing variety of appendages, including scales, feathers, hair follicles, sweat glands, mammary glands (Figure 1). These organs arise from embryonic progenitor cells endow wide-ranging properties, regulation body temperature, ability fly, nurse young, attract mates. As body's primary frontier, both vulnerable disease, such as melanoma, a source therapeutic promise, harboring accessible stem (SCs) that can regenerate potentially other organs.