Fledertiere und andere Reservoirwirte der Filoviridae. Epidemiegefahr am afrikanischen Kontinent? – Eine deduktive Literaturanalyse

摘要: Ebola and Marburg virus, forming the Filoviridae family, cause hemorrhagic fever in countries of sub-Saharan Africa. These viral diseases are characterized by a sudden epidemic occurrence as well high lethality. Even though reservoir host has not been approved yet, literature indicates order bats (Chiroptera) potential host. Significant references lead to delineation hypothetical ecosystem including Chiroptera. IgG-specific Ebola-Zaire antibodies were detected Hammer-headed Bats (Hypsignathus monstrosus), Epauletted Fruit (Epomops franqueti), Little Collared (Myonycteris torquata) during outbreaks between 2001 2005 Gabon Republic Congo. The discovery IgG-specific-Marburg virus virus-specific ribonucleic acid Egyptian (Rousettus aegyptiacus) provided further indication for exploration In 2007, isolation could first time be accomplished directly from apparently healthy naturally infected Kitaka Mine (Uganda). Risk groups can defined through chronological reprocessing interpretation existing epidemic-outbreaks on African continent search infection reasons index cases. following risk factors an with or must put into consideration: Contact consumption wild animal carcasses, sightseeing caves work mines. focus this review is demonstration profiles their exposure Chiroptera other hosts.