The kidney and hypertension: novel insights from transgenic models.
作者： Marcela Herrera , Thomas M. Coffman
DOI: 10.1097/MNH.0B013E3283503068
关键词:
摘要: Purpose of reviewDespite decades study, the pathogenesis essential hypertension remains obscure, but kidney appears to play a central role. Technology for manipulation mouse genome has been immensely valuable in dissecting pathways involved blood pressure control. This review sum
wkhealth.com参考文章(39)
Vanesa D. Ramseyer, Pablo D. Cabral, Jeffrey L. Garvin, Role of endothelin in thick ascending limb sodium chloride transport. Contributions To Nephrology. ,vol. 172, pp. 76- 83 ,(2011) , 10.1159/000328686
Ye Zhang, Pedro A. Jose, Chunyu Zeng, Regulation of sodium transport in the proximal tubule by endothelin. Contributions To Nephrology. ,vol. 172, pp. 63- 75 ,(2011) , 10.1159/000328684
Jeffrey L. Garvin, Angiotensin stimulates bicarbonate transport and Na+/K+ ATPase in rat proximal straight tubules. Journal of The American Society of Nephrology. ,vol. 1, pp. 1146- 1152 ,(1991) , 10.1681/ASN.V1101146
L Gabriel Navar, Minolfa C Prieto, Ryousuke Satou, Hiroyuki Kobori, Intrarenal angiotensin II and its contribution to the genesis of chronic hypertension Current Opinion in Pharmacology. ,vol. 11, pp. 180- 186 ,(2011) , 10.1016/J.COPH.2011.01.009
James A. McCormick, Kerim Mutig, Joshua H. Nelson, Turgay Saritas, Ewout J. Hoorn, Chao-Ling Yang, Shaunessy Rogers, Joshua Curry, Eric Delpire, Sebastian Bachmann, David H. Ellison, A SPAK isoform switch modulates renal salt transport and blood pressure. Cell Metabolism. ,vol. 14, pp. 352- 364 ,(2011) , 10.1016/J.CMET.2011.07.009
Vladislav Bugaj, Elena Mironova, Donald E. Kohan, James D. Stockand, Collecting duct-specific endothelin b receptor knockout increases enac activity American Journal of Physiology-cell Physiology. ,vol. 302, ,(2012) , 10.1152/AJPCELL.00301.2011
Marcela Herrera, Jeffrey L. Garvin, A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1. American Journal of Physiology-renal Physiology. ,vol. 288, ,(2005) , 10.1152/AJPRENAL.00209.2004
Marcela Herrera, Nancy J Hong, Pablo A Ortiz, Jeffrey L Garvin, None, Endothelin-1 Inhibits Thick Ascending Limb Transport via Akt-stimulated Nitric Oxide Production Journal of Biological Chemistry. ,vol. 284, pp. 1454- 1460 ,(2009) , 10.1074/JBC.M804322200
Carie S. Facemire, Mytrang Nguyen, Leigh Jania, William H. Beierwaltes, Hyung-Suk Kim, Beverly H. Koller, Thomas M. Coffman, A major role for the EP4 receptor in regulation of renin. American Journal of Physiology-renal Physiology. ,vol. 301, ,(2011) , 10.1152/AJPRENAL.00054.2011
Jazmin M. Perez-Rojas, Kamal M. Kassem, William H. Beierwaltes, Jeffrey L. Garvin, Marcela Herrera, Nitric oxide produced by endothelial nitric oxide synthase promotes diuresis American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 298, ,(2010) , 10.1152/AJPREGU.00181.2009