The Association Between Corticomotor Excitability and Motor Skill Learning in People With Painful Hand Arthritis.

摘要: OBJECTIVES Previous studies have shown a tendency for reduced motor cortex inhibition in chronic pain populations. People with also routinely demonstrate deficiencies, including skill learning. The goals of the current study were to (1) provide thorough analysis corticomotor and intracortical excitability people arthritic hand pain, (2) examine relationship between these measures performance on learning task. METHODS Twenty-three 20 pain-free controls participated cross-sectional study. Transcranial magnetic stimulation was used assess first dorsal interosseus muscle. Participants then completed 30-minute training task involving index finger same hand. RESULTS Hand arthritis participants showed evidence enhanced facilitation, which correlated duration pain. Arthritis initially poorer at but over total time equivalent groups. There no associations found DISCUSSION Our findings are cortical disinhibition painful arthritis, as previously demonstrated other Cortical changes may progress longer persists, increased being associated greater disinhibition. that related impaired function or