Group B streptococcal epidemiology and vaccine needs in developed countries

摘要: Development of a group B streptococcal vaccine (GBS) is the most promising approach for prevention GBS infections in babies, given potential adverse effects intrapartum antibiotic prophylaxis as well need effective both adult and late perinatal disease. There are numerous strategies at this time but none 100% eradication neonatal early onset disease there no preventative The therefore, utmost importance. Efforts applying genomics to development have led identification novel candidates. publication whole genomes coupled with new technologies including multigenome screening bioinformatics has also allowed researchers overcome serotype limitation earlier preparations search universal against GBS. This review brings together key arguments concerning developed countries describes current status epidemiology microbiology these countries.