pH is a Neurally Regulated Physiological System. Increased Acidity Alters Protein Conformation and Cell Morphology and is a Significant Factor in the Onset of Diabetes and Other Common Pathologies

摘要: Background: The body's physiological stability is maintained by the influence of autonomic nervous system and dynamic interaction organ systems which regulate all aspects function. These their function have been overlooked genetic paradigm. A better understanding these may lead to an improved fundamental relationship involving sense perception, neural networks, cellular molecular biology. This article follows earlier articles author illustrate that sleep, blood pressure glucose are neurally regulated systems. Aims: purpose this discuss how Grakov's mathematical model (i) influences contemporary processes pH in biological i.e. a system; (ii) significant factor emergence changes cell morphology and, ultimately, onset pathologies; (iii) involves environmental factors more commonly associated with phenotype. Results: It considers role played e.g. regulating levels redox state minerals, protein conformation, activation proteins enzymes, metabolic consequences increased acidity, particular from alcoholic beverages acidified soft drinks, stability. Conclusions: concludes impaired ability its exascerbated consumption highly acidic beverages, considerably underestimated subsequent development many common pathologies diabetes, cardiovascular diseases, alzheimer's disease, cancers, etc.