The relationship between serum biotin and oxidant/antioxidant activities in bovine lameness

摘要: Abstract Serum biotin concentrations, erythrocyte superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), reduced (GSH) and plasma thiobarbituric acid reactive substances (TBARS) were measured in 36 dairy cows, 18 of them healthy served as control. In the cows with lameness problems, there 5 interdigital necrobacillosis, subsolar abscessation, 2 solar ulcers, white line disease, chronic laminitis septic arthritis. The degree was estimated to be slight 3 moderate 11 severe 4 cows. Plasma fibrinogen levels TBARS concentrations increased significantly ( P  ⩽ 0.05) lame compared control group. antioxidant enzymes GSH-Px, CAT level activity SOD decreased affected ones. ranged from 2.25 3.5 ng/ml while 1.17 2.3 ng/ml. Biotin correlated positively blood GSH r  = 0.870,  ⩽ 0.05),  = 0.735, GSH-Px  = 0.539,  = 0.637,  = 0.449,  = 0.533,  = 0.585, both subjects, respectively.