Cholesterol and Hydroxycholesterol in the Brain

作者: Akhlaq A. Farooqui

DOI: 10.1007/978-1-4419-9940-5_10

关键词:

摘要: The brain has higher concentration of cholesterol compared to other body parts (25% the body’s free cholesterol) (Dietschy and Turley, 2004). In brain, resides in two pools: one major pool associated with myelin sheaths playing an important role propagation electrical signals along axons minor plasma membranes astrocytes neurons

参考文章(141)
Jason Y. Chang, Kevin D. Phelan, Ling-Zhi Liu, Neurotoxicity of 25-OH-Cholesterol on NGF-Differentiated PC12 Cells Neurochemical Research. ,vol. 23, pp. 7- 16 ,(1998) , 10.1023/A:1022437000893
Radosveta P. Koldamova, Iliya M. Lefterov, Milos D. Ikonomovic, John Skoko, Preslav I. Lefterov, Barbara A. Isanski, Steven T. DeKosky, John S. Lazo, 22R-Hydroxycholesterol and 9-cis-Retinoic Acid Induce ATP-binding Cassette Transporter A1 Expression and Cholesterol Efflux in Brain Cells and Decrease Amyloid β Secretion Journal of Biological Chemistry. ,vol. 278, pp. 13244- 13256 ,(2003) , 10.1074/JBC.M300044200
Gurdeep Marwarha, Bhanu Dasari, Jaya RP Prasanthi, Jared Schommer, Othman Ghribi, None, Leptin Reduces the Accumulation of Aβ and Phosphorylated Tau Induced by 27-Hydroxycholesterol in Rabbit Organotypic Slices Journal of Alzheimer's Disease. ,vol. 19, pp. 1007- 1019 ,(2010) , 10.3233/JAD-2010-1298
Zhi-Xing Yao, Rachel C. Brown, Gary Teper, Janet Greeson, Vassilios Papadopoulos, 22R‐Hydroxycholesterol protects neuronal cells from β‐amyloid‐induced cytotoxicity by binding to β‐amyloid peptide Journal of Neurochemistry. ,vol. 83, pp. 1110- 1119 ,(2002) , 10.1046/J.1471-4159.2002.01202.X
Lloyd Horrocks, Akhlaq Farooqui, Wei-Yi Ong, Comprar Neurochemical Aspects of Excitotoxicity | Farooqui, Akhlaq | 9780387730226 | Springer Springer. ,(2008)
O Masumoto, Y Ohyama, K Okuda, Purification and characterization of vitamin D 25-hydroxylase from rat liver mitochondria. Journal of Biological Chemistry. ,vol. 263, pp. 14256- 14260 ,(1988) , 10.1016/S0021-9258(18)68214-6
Werner J. Kovacs, Phyllis L. Faust, Gilbert-Andre Keller, Skaidrite K. Krisans, Purification of brain peroxisomes and localization of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase FEBS Journal. ,vol. 268, pp. 4850- 4859 ,(2001) , 10.1046/J.0014-2956.2001.02409.X
George J. Schroepfer, Oxysterols: modulators of cholesterol metabolism and other processes. Physiological Reviews. ,vol. 80, pp. 361- 554 ,(2000) , 10.1152/PHYSREV.2000.80.1.361
Makoto Michikawa, Neurodegenerative disorders and cholesterol. Current Alzheimer Research. ,vol. 1, pp. 271- 275 ,(2004) , 10.2174/1567205043331983