The effects of cyclobenzaprine on sleep physiology and symptoms in patients with fibromyalgia.

摘要: A double blind, placebo controlled, crossover design study examined overnight sleep physiology, pain, fatigue, and mood symptoms in 12 patients with fibromyalgia treated cyclobenzaprine. Nine completed the study. Patients receiving cyclobenzaprine showed a decrease evening fatigue (F = 4.7, p less than 0.05) an increase total time 4.4, 0.05). Pain, including tender point count dolorimetry, ratings, alpha non-REM EEG anomaly were unchanged by