Three-year canaloplasty outcomes for the treatment of open-angle glaucoma: European study results

摘要: To report 3-year results investigating the safety and efficacy of canaloplasty, a procedure involving circumferential viscodilation Schlemm’s canal tensioning inner wall to treat open-angle glaucoma. This was prospective, multi-center, interventional study 109 eyes adult, glaucoma patients undergoing canaloplasty or combined cataract-canaloplasty surgery. Qualifying preoperative intraocular pressures (IOP) were at least 16 mmHg with historical IOPs 21 mmHg without medical therapy. A flexible microcatheter used viscodilate full circumference place trabecular suture. Primary outcome measures included IOP, medication usage, adverse events. Eyes showed mean baseline IOP 23.0 ± 4.3 mmHg usage 1.9 ± 0.7 medications, which decreased 15.1 ± 3.1 mmHg on 0.9 ± 0.9 medications 3 years postoperatively. surgery 24.3 ± 6.0 mmHg 1.5 ± 1.2 13.8 ± 3.2 mmHg 0.5 ± 0.7 3 years. Intraocular pressure use for all significantly from (p <0.00001) intervals. Late postoperative complications cataracts (19.1%) transient elevation (1.8%). Canaloplasty demonstrated significant sustained reductions accompanied by an excellent short- long-term profile in adult