IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase.

作者: M. Los , H. Schenk , K. Hexel , P. A. Baeuerle , W. Dröge

DOI: 10.1002/J.1460-2075.1995.TB00043.X

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摘要: … , strongly induced IL-2 production. The enhancement of IL-2 gene expression by the CD28 … ) localized at position -162 to -152 within the IL-2 promoter (Fraser et al., 1991; Verweij et al., …

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