作者: Richard V. Milani , Carl J. Lavie
DOI: 10.1016/J.AMJMED.2007.03.026
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摘要: Abstract Purpose Depression following major cardiac events is associated with higher mortality, but little known about whether this can be reduced through treatment including rehabilitation and exercise training. We evaluated the impact of on depression its mortality in coronary patients. Patients Methods 522 consecutive patients (381 men, 141 women; aged 64±10 years) enrolled from January 2000 to July 2005 a control group 179 not completing rehabilitation. Depressive symptoms were assessed by questionnaire at baseline rehabilitation, was after mean follow-up 1296±551 days. Results Prevalence depressive decreased 63% 17% 6% ( P =.0004). Depressed who completed had 73% lower (8% vs 30%; =.0005) compared depressed subjects did complete Reductions related improvements fitness; however, similar reductions noted those either modest or marked increases capacity. Conclusion In events, both excess it. Moreover, only mild levels fitness appear needed produce these benefits mortality.