Reduction of ventriculostomy-associated CSF infection with antibiotic-impregnated catheters in pediatric patients: a single-institution study.

摘要: Objective External ventricular drains (EVDs) are commonly used in the neurosurgical population. However, very few pediatric neurosurgery studies available regarding EVD-associated infection rates with antibiotic-impregnated EVD catheters. The authors previously published a large cohort study analyzing nonantibiotic-impregnated catheters and risk factors associated infections. In this study, they aimed to analyze rate after implementation of Methods A retrospective observational patients (younger than 18 years age) who underwent burr hole for placement were admitted quaternary care ICU between January 2011 2019 reviewed. ventriculostomy-associated was compared authors' historical control Results Two hundred twenty-nine identified. Neurological diagnostic categories included externalization an existing shunt (externalized shunt) 34 (14.9%); brain tumor (tumor) 77 (33.6%); intracranial hemorrhage (ICH) 27 (11.8%); traumatic injury (TBI) 6 (2.6%); 85 (37.1%) captured "other" category. 229 (0.9% all patients) had CSF infections management, totaling 0.99 per 1000 catheter days. This is significantly lower reported analysis use vs 6%, p = 0.00128). Conclusions their cohort, demonstrated significant decline at institution.