Facile preparation of nuclease resistant 3′ modified oligodeoxynucleotides

作者: Howard B. Gamper , Michael W. Reed , Thomas Cox , Jeanne S. Virosco , A. David Adams

DOI: 10.1093/NAR/21.1.145

关键词:

摘要: … and that a single modified linkage is sufficient to inhibit these enzymes. Compared to their fully modified homologs, ODNs with terminal backbone modifications form more stable DNA-…

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