Method of increasing viral growth rate and/or titre in cells

作者: Richard E Randall , Claire Stewart , Catherine S Adamson

DOI:

关键词:

摘要: Methods of increasing viral growth rate and/or titre in cell culture. A method cells for virus production, through the use inhibitors interferon induction signalling cascade.

参考文章(21)
Derek G. Ostertag, Douglas J. Jolly, Ryan S. Burnett, Joan M. Robbins, Tiffany Huang, Harry E. Gruber, Amy H. Lin, Enhanced cancer treatment and monitoring using recombinant vectors ,(2011)
L. Didcock, D. F. Young, S. Goodbourn, R. E. Randall, Sendai Virus and Simian Virus 5 Block Activation of Interferon-Responsive Genes: Importance for Virus Pathogenesis Journal of Virology. ,vol. 73, pp. 3125- 3133 ,(1999) , 10.1128/JVI.73.4.3125-3133.1999
Thomas J. Chambers, Thomas P. Monath, Farshad Guirakhoo, Chimeric Flavivirus Vaccines ,(1998)
Shruthi Naik, Stephen J Russell, Engineering oncolytic viruses to exploit tumor specific defects in innate immune signaling pathways Expert Opinion on Biological Therapy. ,vol. 9, pp. 1163- 1176 ,(2009) , 10.1517/14712590903170653
Biao He, Reay G. Paterson, Nicola Stock, Joan E. Durbin, Russell K. Durbin, Stephen Goodbourn, Richard E. Randall, Robert A. Lamb, Recovery of Paramyxovirus Simian Virus 5 with a V Protein Lacking the Conserved Cysteine-rich Domain: The Multifunctional V Protein Blocks both Interferon-β Induction and Interferon Signaling Virology. ,vol. 303, pp. 15- 32 ,(2002) , 10.1006/VIRO.2002.1738
D. F. Young, L. Andrejeva, A. Livingstone, S. Goodbourn, R. A. Lamb, P. L. Collins, R. M. Elliott, R. E. Randall, Virus replication in engineered human cells that do not respond to interferons. Journal of Virology. ,vol. 77, pp. 2174- 2181 ,(2003) , 10.1128/JVI.77.3.2174-2181.2003
Adolfo García-Sastre, Andrej Egorov, Demetrius Matassov, Sabine Brandt, David E Levy, Joan E Durbin, Peter Palese, Thomas Muster, None, Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems Virology. ,vol. 252, pp. 324- 330 ,(1998) , 10.1006/VIRO.1998.9508
Otto Haller, Georg Kochs, Friedemann Weber, The interferon response circuit: Induction and suppression by pathogenic viruses Virology. ,vol. 344, pp. 119- 130 ,(2006) , 10.1016/J.VIROL.2005.09.024
Saurabh Chattopadhyay, Ganes C. Sen, IRF-3 and Bax: a deadly affair. Cell Cycle. ,vol. 9, pp. 2479- 2480 ,(2010) , 10.4161/CC.9.13.12237