Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice.

摘要: Objectives Based on the recent findings from animal studies, it has been proposed that therapeutic use of valnoctamide, an anxiolytic drug developed in early 1960s, be extended to treat other neurological disorders such as epilepsy and bipolar disease. Given scarcity adequate data its prenatal toxicity, a comparative teratogenicity study valnoctamide two most commonly used drugs disorder, risperidone olanzapine, was carried out mouse model system.