Pharmacokinetic Interaction Study of Ranitidine and Daijokito in Healthy Volunteers.
作者： Satoshi Tsuno , Yusuke Endo , Yoshitaka Ishihara , Norimasa Miura , Akiko Matsuda
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摘要: Background Ranitidine is a histamine 2 receptor antagonist, and daijokito Kampo (Chinese herbal medicine as practiced in Japan) formula, which traditionally used for treating constipation digestive trouble. Previous study demonstrated that significantly affected the pharmacokinetics of ranitidine rats; however, doses were higher than clinical practice. Therefore, we examined pharmacokinetic interaction between practice healthy volunteers.
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