Oxidative stress and role of antioxidants in normal and abnormal sperm function

摘要: Defective sperm function is the most common cause of infertility, and until recently, it was difficult to evaluate treat. Part this difficulty due our incomplete understanding factors contributing normal abnormal leading male infertility. Mammalian spermatozoa membranes are rich in high unsaturated fatty acids sensitive oxygen induced damage mediated by lipid peroxidation. Limited endogenous mechanisms exist reverse these damages. The excessive generation reactive species (ROS) contaminating leukocytes (leukocytospermia) has been identified as one few defined etiologies for In a situation, seminal plasma contains antioxidant which likely quench ROS protect against any spermatozoa. However, during genitourinary infection/inflammation may downplay create situation called oxidative stress. addition, aging environmental toxicants also further induce Assessment such stress status (OSS) help medical treatment factor infertility suitable antioxidants.