A simplified approach to minimally invasive parathyroidectomy

摘要: Objectives/Hypothesis To assess the feasibility of a simplified approach for use rapid intraoperative parathyroid hormone (IOPTH) assay based on single 10-minute post-excision level using workup (wPTH) as baseline in minimally invasive parathyroidectomy (MIP) and to compare predictive value this criterion with other recommended criteria. Study Design Case series chart review. Methods A surgeon's prospectively maintained database at an academic center was reviewed over 2-year period from June 2009 through 2011. Results A total 102 patients undergoing MIP met inclusion criteria. An IOPTH threshold ≥50% drop 10 minutes wPTH resulted acceptable false positive (1.9%) negative (0.9%) rates. The sensitivity, specificity, value, accuracy modified 98.9%, 71.4%, 98%, 83.3%, 97%, respectively. Conclusions In our patient cohort, pre-incision pre-excision levels did not seem change overall predicting surgical success if is used along wPTH, commensurate commonly Miami Vienna A blood sample demonstrating should be explored further feasible that avoids multiple samples Level Evidence 4. Laryngoscope, 124:2205–2210, 2014