The Effect of Renal Scarring on Spontaneous Resolution and Breakthrough Infection in Children with Vesicoureteral Reflux
作者： Jong Ho Jeon , Kyung Hun Lee , Jae Shin Park
DOI: 10.4111/KJU.2009.50.7.699
关键词:
摘要: Purpose: Primary treatment of children with vesicoureteral reflux (VUR) is antibiotic prophylaxis until the resolves. But, it not easy to determine in which patients We sought whether renal scarring could help predict prognosis regarding resolution and breakthrough infection. Materials Methods: A total 90 children, 54 boys 36 girls, mean age 15.1 (range: 1-98) months, VUR were analyzed retrospectively. Eighty-six presented febrile urinary tract infection (UTI) 4 prenatal hydronephrosis. Technetium Tc 99m dimercaptosuccinic acid (DMSA) scans performed at months after a UTI. All initially treated (BactrimR; TMX-SMX 2 mg/kg/day) 40 underwent antireflux surgery. Median follow-up was 26.1 6-52) months. Reflux grade defined by use International Classification System. incidence according grade, resolution, reason for Results: Normal DMSA documented 63 (70%) 27 (30%). Children high (III-V) VUR. resolved spontaneously increased risk Renal however, did reflux. Conclusions: conclude that has low spontaneous rate This information would be helpful when counseling families (Korean J Urol 2009;50:699-703)
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