Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases

作者: Paul E O'Maille , Arthur Malone , Nikki Dellas , B Andes Hess , Lidia Smentek

DOI: 10.1038/NCHEMBIO.113

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摘要: Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases | Nature Chemical Biology … 2.nature chemical biology 3.articles …

参考文章(34)
Gerald A. Rosenthal, Daniel H. Janzen, Herbivores: Their Interaction With Secondary Plant Metabolites ,(1982)
Paul E. O'Maille, Ming-Daw Tsai, Bryan T. Greenhagen, Joseph Chappell, Joseph P. Noel, Gene library synthesis by structure-based combinatorial protein engineering. Methods in Enzymology. ,vol. 388, pp. 75- 91 ,(2004) , 10.1016/S0076-6879(04)88008-X
Paul E. O’Maille, Joe Chappell, Joseph P. Noel, A single-vial analytical and quantitative gas chromatography–mass spectrometry assay for terpene synthases Analytical Biochemistry. ,vol. 335, pp. 210- 217 ,(2004) , 10.1016/J.AB.2004.09.011
H. V. Thulasiram, H. K. Erickson, C. D. Poulter, Chimeras of two isoprenoid synthases catalyze all four coupling reactions in isoprenoid biosynthesis. Science. ,vol. 316, pp. 73- 76 ,(2007) , 10.1126/SCIENCE.1137786
S Copley, Enzymes with extra talents: moonlighting functions and catalytic promiscuity Current Opinion in Chemical Biology. ,vol. 7, pp. 265- 272 ,(2003) , 10.1016/S1367-5931(03)00032-2
Patrick J O'Brien, Daniel Herschlag, Catalytic promiscuity and the evolution of new enzymatic activities Chemistry & Biology. ,vol. 6, ,(1999) , 10.1016/S1074-5521(99)80033-7
P. Ross Wilderman, Reuben J. Peters, A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase. Journal of the American Chemical Society. ,vol. 129, pp. 15736- 15737 ,(2007) , 10.1021/JA074977G
Yasuo Yoshikuni, Thomas E. Ferrin, Jay D. Keasling, Designed divergent evolution of enzyme function. Nature. ,vol. 440, pp. 1078- 1082 ,(2006) , 10.1038/NATURE04607
Daniel M Weinreich, Nigel F Delaney, Mark A DePristo, Daniel L Hartl, Darwinian evolution can follow only very few mutational paths to fitter proteins. Science. ,vol. 312, pp. 111- 114 ,(2006) , 10.1126/SCIENCE.1123539
Shimon Bershtein, Michal Segal, Roy Bekerman, Nobuhiko Tokuriki, Dan S. Tawfik, Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein Nature. ,vol. 444, pp. 929- 932 ,(2006) , 10.1038/NATURE05385