Advances, Promises, and Challenges in HIV Prevention

摘要: As there are over two million new HIV infections each year, is a critical need for effective prevention strategies. Over the past 3 decades, studies have tested efficacy of numerous biomedical interventions that been developed to complement existing behavioral Until recently, few these were sufficiently efficacious merit broad implementation. However, several years, groundbreaking demonstrated primary and secondary interventions, which has revitalized field prevention. These promising include administration antiretroviral medications high-risk HIV-uninfected persons, known as preexposure prophylaxis, early treatment HIV-infected persons reduce their infectiousness, strategy referred “Treatment Prevention.” Voluntary medical male circumcision represents an additional intervention be undergoing scale-up in regions with generalized epidemics. faces barriers achieving optimal effectiveness, such substantial adherence challenges resulting conflicting results structural scaling-up therapy Treatment Prevention, cultural increasing uptake communities where practice not normative. If can overcome through scientific creativity, perseverance, political will, combination could help curb epidemic.