The Benefit of Adjuvant Radiation in Surgically-Treated T1-2 N1 Oropharyngeal Squamous Cell Carcinoma.
作者： Marcus M. Monroe , Luke O. Buchmann , Jason P. Hunt , Ying J. Hitchcock , Shane Lloyd
DOI: 10.1002/LIO2.64
关键词:
摘要: Importance The benefit of adjuvant radiation in surgically treated T1-2N1 oropharyngeal cancer without adverse pathologic features remains unclear Objectives To compare population-level survival outcomes surgically-treated squamous cell carcinoma (OPSCC) with and the use radiation. Study Design Retrospective population-based study using Surveillance, Epidemiology, End Results (SEER) registry data from 1998–2011. Setting Population-level study. Participants Patients OPSCC surgical resection neck dissection or radiation. Intervention(s) for Clinical Trials Exposure(s) observational studies The postoperative radiation. Main Outcome(s) Measures Overall disease-specific survival. Results Radiation was utilized 74% patients positively associated extracapsular extension well-differentiated histology. The improved mean overall (124 v. 108 months, p=0.023) a non-significant increase (138 131 p=0.053). Conclusions Relevance The is oropharynx unknown HPV status. Level Evidence IV
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