On the descending control of the lumbosacral spinal cord from the "mesencephalic locomotor region".

摘要: Continuous stimulation (60 c/s) of a region below the inferior coliculus can induce locomotion on treadmill precollicular, postmammilar cats. This study aims at revealing what changes occur in spinal cord, when “locomotor region” is stimulated. enables cat to walk if moved. After controlling threshold for evoking good locomotion, cats were curarized. Stimulation strength that evoked walking prior curarization induced depression inhibitory short-latency reflex effects α-motoneurones from cutaneous, and high muscular afferents without changing direct excitability α-motoneurones. The longlasting reciprocally organized discharges was lowered. results suggest are by slow fiber system, releases activity stepping generating neurones. would be explained noradrenergic reticulospinal system activated mesencephalic locomotor region.