Benign familial recurrent intrahepatic cholestasis

摘要: Three new cases of benign familial recurrent intrahepatic cholestasis in a brother, sister, and mother are reported. These emphasize the nature disorder characteristic clinical findings attacks, cholestatic jaundice, pruritus with increases serum bilirubin, increased alkaline phosphatase. A normal extrahepatic biliary tree was shown by dye studies, liver biopsy showed central lobular without any inflammation or necrosis. Liver function tests were between attacks. This condition must be differentiated from obstruction, parenchymal disease, drug-induced other types jaundice.