Cu-mediated C2-dehydrogenative homocoupling of indoles via C–H activation assisted by a removable N-pyrimidyl group
作者： Jun Le , Yadong Gao , Yousong Ding , Chao Jiang
DOI: 10.1016/J.TETLET.2016.03.027
关键词:
摘要: Abstract A Cu-mediated regioselective, dehydrogenative homocoupling of indoles was developed using AgNO3 as the additive. The easily installed and removed N-pyrimidyl group exerted complete C2 regiocontrol via C–H activation. series indole substrates underwent cross-dehydrogenative-homocoupling. This work an effective approach for synthesis 2,2′-biindole core a number chemicals fundamentally important in material pharmaceutical chemistry.
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