Molecular Recognition of Protein Kinase Binding Pockets for Design of Potent and Selective Kinase Inhibitors

作者: Jeffrey Jie-Lou Liao

DOI: 10.1021/JM0608107

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摘要: … kinase domain was determined for cAMP-dependent kinase (PKA) in 1991. To address the issue of how to design highly potent and selective kinase inhibitors… protein kinase targets and …

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