Insights and inferences about integron evolution from genomic data

作者: Diana R Nemergut , Michael S Robeson , Robert F Kysela , Andrew P Martin , Steven K Schmidt

DOI: 10.1186/1471-2164-9-261

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摘要: Background Integrons are mechanisms that facilitate horizontal gene transfer, allowing bacteria to integrate and express foreign DNA. These important in the exchange of antibiotic resistance determinants, but can also transfer a diverse suite genes unrelated pathogenicity. Here, we provide systematic analysis distribution diversity integron intI integron-containing bacteria.

参考文章(64)
Silvia Szekeres, Mira Dauti, Caroline Wilde, Didier Mazel, Dean A. Rowe-Magnus, Chromosomal toxin-antitoxin loci can diminish large-scale genome reductions in the absence of selection. Molecular Microbiology. ,vol. 63, pp. 1588- 1605 ,(2007) , 10.1111/J.1365-2958.2007.05613.X
Karen E. Nelson, Rebecca A. Clayton, Steven R. Gill, Michelle L. Gwinn, Robert J. Dodson, Daniel H. Haft, Erin K. Hickey, Jeremy D. Peterson, William C. Nelson, Karen A. Ketchum, Lisa McDonald, Teresa R. Utterback, Joel A. Malek, Katja D. Linher, Mina M. Garrett, Ashley M. Stewart, Matthew D. Cotton, Matthew S. Pratt, Cheryl A. Phillips, Delwood Richardson, John Heidelberg, Granger G. Sutton, Robert D. Fleischmann, Jonathan A. Eisen, Owen White, Steven L. Salzberg, Hamilton O. Smith, J. Craig Venter, Claire M. Fraser, Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima Nature. ,vol. 399, pp. 323- 329 ,(1999) , 10.1038/20601
Yan Boucher, CamillaL Nesbø, MichaelJ Joss, Andrew Robinson, BridgetC Mabbutt, MichaelR Gillings, W Ford Doolittle, HW Stokes, Recovery and evolutionary analysis of complete integron gene cassette arrays from Vibrio BMC Evolutionary Biology. ,vol. 6, pp. 3- 3 ,(2006) , 10.1186/1471-2148-6-3
Ruth M. Hall, Andrew J. Holmes, Paul H. Roy, H. W. Stokes, What are superintegrons Nature Reviews Microbiology. ,vol. 5, pp. 1- 2 ,(2007) , 10.1038/NRMICRO1462-C1
S. Nandi, J. J. Maurer, C. Hofacre, A. O. Summers, Gram-positive bacteria are a major reservoir of Class 1 antibiotic resistance integrons in poultry litter Proceedings of the National Academy of Sciences of the United States of America. ,vol. 101, pp. 7118- 7122 ,(2004) , 10.1073/PNAS.0306466101
T. Z. DeSantis, P. Hugenholtz, N. Larsen, M. Rojas, E. L. Brodie, K. Keller, T. Huber, D. Dalevi, P. Hu, G. L. Andersen, Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB Applied and Environmental Microbiology. ,vol. 72, pp. 5069- 5072 ,(2006) , 10.1128/AEM.03006-05
Andrew J. Holmes, Marita P. Holley, Andrew Mahon, Blair Nield, Michael Gillings, H. W. Stokes, Recombination Activity of a Distinctive Integron-Gene Cassette System Associated with Pseudomonas stutzeri Populations in Soil Journal of Bacteriology. ,vol. 185, pp. 918- 928 ,(2003) , 10.1128/JB.185.3.918-928.2003
Didier Mazel, Broderick Dychinco, Vera A Webb, Julian Davies, A Distinctive Class of Integron in the Vibrio cholerae Genome Science. ,vol. 280, pp. 605- 608 ,(1998) , 10.1126/SCIENCE.280.5363.605
Gavin D. Recchia, H.W. Stokes, Ruth M. Hall, Characterisation of specific and secondary recombination sites recognised by the integron DNA integrase Nucleic Acids Research. ,vol. 22, pp. 2071- 2078 ,(1994) , 10.1093/NAR/22.11.2071
Evgeniy S. Balakirev, Francisco J. Ayala, Pseudogenes: are they "junk" or functional DNA? Annual Review of Genetics. ,vol. 37, pp. 123- 151 ,(2003) , 10.1146/ANNUREV.GENET.37.040103.103949