Estimating true evolutionary distances under rearrangements, duplications, and losses
作者： Yu Lin , Vaibhav Rajan , Krister M Swenson , Bernard ME Moret
DOI: 10.1186/1471-2105-11-S1-S54
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摘要: Background The rapidly increasing availability of whole-genome sequences has enabled the study evolution. Evolutionary mechanisms based on genome rearrangements have attracted much attention and given rise to many models; somewhat independently, gene duplication loss seen work. However, two are not independent thus require a unified treatment, which remains missing date. Moreover, existing rearrangement models do fit dichotomy between most prokaryotic genomes (one circular chromosome) eukaryotic (multiple linear chromosomes).
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