A comparison between track-structure, condensed-history Monte Carlo simulations and MIRD cellular S-values.

摘要: The S-value is a standard measure in cellular dosimetry. S-values are calculated by applying analytical methods or Monte Carlo simulation. In simulation, particles either tracked individually event-by-event close events condensed and processed collectively different steps. Both of these have been employed for estimation S-values, but there no consistency between the published results. present paper, we used Geant4-DNA track-structure physics model as reference to estimate S-values. We compared results with corresponding values obtained from following three condensed-history models Geant4: Penelope, Livermore standard. geometry source were exactly same all simulations. utilized mono-energetic electrons an initial kinetic energy range 1-700 keV radiation. also our MIRD first drew overall comparison data series then dependence on size scoring compartments. indicated very good linear correlation (R 2  >  91%) small bias (3%) model. simulation was considerable (-8%). However, point-by-point revealed differences up 28% MC codes self-absorption 10-50 keV range. For cross-absorption difference 34%. this range, 68%. Our findings suggest that consistency/inconsistency simulations depends volumes, particles, step-size electron tracking cutoff codes.